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The 14 CUB Repeats and their Active sites

S.NO	Uniprot ID	Protein Name	Sequence Length	CUB Region	Active Site	Involvement of Repeats in Active site
1	Q7RTY8	Transmembrane protease serine 7	843	DOMAIN 247 360 CUB 1 DOMAIN 365 481 CUB 2	ACT_SITE 646 646 Charge relay system ACT_SITE 694 694 Charge relay system ACT_SITE 790 790 Charge relay system	N
2	P13497	Bone morphogenetic protein 1	986	DOMAIN 322 434 CUB 1 DOMAIN 435 546 CUB 2 DOMAIN 591 703 CUB 3 DOMAIN 747 859 CUB 4 DOMAIN 860 976 CUB 5	ACT_SITE 214 214	N
3	O43897	Tolloid-like protein 1	1013	DOMAIN 349 461 CUB 1 DOMAIN 462 574 CUB 2 DOMAIN 618 730 CUB 3 DOMAIN 774 886 CUB 4 DOMAIN 887 1003 CUB 5	ACT_SITE 241 241	N
4	Q9Y6L7	Tolloid-like protein 2	1015	DOMAIN 351 463 CUB 1 DOMAIN 464 576 CUB 2 DOMAIN 620 732 CUB 3 DOMAIN 776 888 CUB 4 DOMAIN 889 1005 CUB 5	ACT_SITE 243 243	N
5	P09871	Complement C1s subcomponent	688	DOMAIN 16 130 CUB 1 DOMAIN 175 290 CUB 2	ACT_SITE 475 475 Charge relay system ACT_SITE 529 529 Charge relay system ACT_SITE 632 632 Charge relay system	N
6	O00187	Mannan-binding lectin serine protease 2	686	DOMAIN 16 137 CUB 1 DOMAIN 184 296 CUB 2	ACT_SITE 483 483 Charge relay system ACT_SITE 532 532 Charge relay system ACT_SITE 633 633 Charge relay system	N
7	P00736	Complement C1r subcomponent	705	DOMAIN 18 141 CUB 1 DOMAIN 193 305 CUB 2	ACT_SITE 502 502 Charge relay system ACT_SITE 557 557 Charge relay system ACT_SITE 654 654 Charge relay system	N
8	P48740	Mannan-binding lectin serine protease 1	699	DOMAIN 20 138 CUB 1 DOMAIN 185 297 CUB 2	ACT_SITE 490 490 Charge relay system ACT_SITE 552 552 Charge relay system ACT_SITE 646 646 Charge relay system	N
9	Q7RTY7	Ovochymase-1	1134	DOMAIN 284 410 CUB 1 DOMAIN 419 531 CUB 2 DOMAIN 846 957 CUB 3	ACT_SITE 87 87 Charge relay system ACT_SITE 139 139 Charge relay system ACT_SITE 237 237 Charge relay system ACT_SITE 615 615 Charge relay system ACT_SITE 664 664 Charge relay system ACT_SITE 763 763 Charge relay system	N
10	Q7RTZ1	Ovochymase-2	564	DOMAIN 311 421 CUB 1 DOMAIN 431 543 CUB 2	ACT_SITE 92 92 Charge relay system ACT_SITE 142 142 Charge relay system ACT_SITE 240 240 Charge relay system	N
11	P98073	Enteropeptidase	1019	DOMAIN 225 334 CUB 1 DOMAIN 524 634 CUB 2	ACT_SITE 825 825 Charge relay system ACT_SITE 876 876 Charge relay system ACT_SITE 971 971 Charge relay system	N
12	Q76LX8	A disintegrin and metalloproteinase with thrombospondin motifs 13	1427	DOMAIN 1192 1298 CUB 1 DOMAIN 1299 1427 CUB 2	ACT_SITE 225 225	N
13	Q8IU80	Transmembrane protease serine 6	811	DOMAIN 213 336 CUB 1 DOMAIN 335 452 CUB 2	ACT_SITE 617 617 Charge relay system ACT_SITE 668 668 Charge relay system ACT_SITE 762 762 Charge relay system	N
14	Q9Y5Y6	Suppressor of tumorigenicity 14 protein	855	DOMAIN 214 334 CUB 1 DOMAIN 340 447 CUB 2	ACT_SITE 656 656 Charge relay system ACT_SITE 711 711 Charge relay system ACT_SITE 805 805 Charge relay system	N