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The 2 FF Repeats and their Mutations

S.NO	Uniprot ID	Protein Name	Sequence Length	FF Region	Mutation	Involvement of Repeats in Mutations
1	O14776	Transcription elongation regulator 1	1098	659 712 DOMAIN 659 712 FF 1 725 779 DOMAIN 725 779 FF 2 791 846 DOMAIN 791 846 FF 3 896 952 DOMAIN 896 952 FF 4 954 1010 DOMAIN 954 1010 FF 5 1012 1077 DOMAIN 1012 1077 FF 6	148 150 148 150 YYY->AAA: Reduces repression of transcription by 35% when associated with 446-AAA-448 446 448 446 448 YYY->AAA: Loss of interaction with SF1 when associated with 148-AAA-150 545 547 545 547 FFY->AAA: No effect	N
2	Q9NRY4	Rho GTPase-activating protein 35	1499	270 327 DOMAIN 270 327 FF 1 368 422 DOMAIN 368 422 FF 2 429 483 DOMAIN 429 483 FF 3 485 550 DOMAIN 485 550 FF 4	1221 1221 S->A: No effect on total phosphorylation levels when associated with A-1226 when associated with A-1126 and A-1236 1221 1221 S->D: Enhances Rac GAP activity 1226 1226 T->A: No effect on total phosphorylation levels when associated with A-1221 when associated with A-1121 and A-1236 1226 1226 T->D: Enhances Rac GAP activity 1236 1236 S->A: No effect on total phosphorylation levels when associated with A-1121 and A-1226	N