| S.NO | Uniprot ID | Protein Name | Sequence Length | IPT/TIG Region | Mutation | Involvement of Repeats in Mutations |
| 1 | O15031 | Plexin-B2 | 1838 | 1161 1164
1161 1164 RQKR->AQKA: Abolishes cleavage by proprotein convertases | N | |
| 2 | O43157 | Plexin-B1 | 2135 | 139 139 D->K: Strongly reduced interaction with SEMA4D 1302 1305 1302 1305 RRRR->AAAA: Abolishes cleavage by proprotein convertases 1815 1815 L->F,P: Abolishes interaction with RAC1 and RND1 1884 1885 1884 1885 WH->SS: Loss of cytoskeleton remodeling in response to SEMA4D | Y | |
| 3 | P08581 | Hepatocyte growth factor receptor | 1390 | 1234 1234 Y->F: Complete loss of kinase activity and of ligand-induced ubiquitination when associated with F-1235 1235 1235 Y->F: Complete loss of kinase activity when associated with F-1234 1313 1313 Y->F: No effect on ligand-induced CBL-mediated ubiquitination when associated with F-1349, F-1356 and F-1365 1349 1349 Y->F: No effect on ligand-induced CBL-mediated ubiquitination when associated with F-1313, F-1356 and F-1365 1356 1356 Y->F: No effect on ligand-induced CBL-mediated ubiquitination when associated with F-1313, F-1349 and F-1365 1365 1365 Y->F: No effect on ligand-induced CBL-mediated ubiquitination when associated with F-1313, F-1349 and F-1356 | N | |