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The 2 Kringle Repeats and their Mutations

S.NO	Uniprot ID	Protein Name	Sequence Length	Kringle Region	Mutation	Involvement of Repeats in Mutations
1	P00747	Plasminogen	810	103 181 DOMAIN 103 181 Kringle 1 184 262 DOMAIN 184 262 Kringle 2 275 352 DOMAIN 275 352 Kringle 3 377 454 DOMAIN 377 454 Kringle 4 481 560 DOMAIN 481 560 Kringle 5	741 741 S->A: Proteolytically cleaved, but abolishes plasmin activity and cell detachment	N
2	P14210	Hepatocyte growth factor	728	128 206 DOMAIN 128 206 Kringle 1 211 288 DOMAIN 211 288 Kringle 2 305 383 DOMAIN 305 383 Kringle 3 391 469 DOMAIN 391 469 Kringle 4	494 494 R->Q: Loss of activity due to absence of proteolytic cleavage	N