| S.NO | Uniprot ID | Protein Name | Sequence Length | MIF4G Region | Mutation | Involvement of Repeats in Mutations |
| 1 | Q9HAU5 | Regulator of nonsense transcripts 2 | 1272 | 796 797
796 797 RK->EE: Strongly impairs RNA-binding 847 847 D->K: Does not abolish interaction with UPF3B 851 852 851 852 ED->KR: Does not abolish interaction with UPF3B when associated with D-854 854 854 R->D: Does not abolish interaction with UPF3B when associated with K-851 and R-852 858 858 E->R: Abolishes interaction with UPF3B and association with SMG1 and RBM8A reduces phosphorylation of UPF1 894 894 Y->A: Does not impair RNA-binding when associated with A-932 932 932 Y->A: Does not impair RNA-binding when associated with A-894 1113 1113 F->E: Abolishes interaction with UPF1 1120 1120 M->E: Decreases interaction with UPF1 does not reduce NMD efficiency 1121 1121 M->E: Decreases interaction with UPF1 does not reduce NMD efficiency 1123 1123 E->R: Decreases interaction with UPF1 1169 1169 M->E: Decreases interaction with UPF1 1171 1171 F->E: Abolishes interaction with UPF1 reduces NMD efficiency 1171 1171 F->E: Greatly reduces NMD efficiency when associated with E-1173 and E-1174 1173 1173 M->E: Abolishes interaction with UPF1 1173 1173 M->E: Greatly reduces NMD efficiency when associated with E-1171 and E-1174 1174 1174 L->E: Abolishes interaction with UPF1 reduces NMD efficiency 1174 1174 L->E: Greatly reduces NMD efficiency when associated with E-1171 and E-1173 1176 1176 R->E: Decreases interaction with UPF1 | Y |