| S.NO | Uniprot ID | Protein Name | Sequence Length | MBT Repeats region | Mutations | Involvement of Repeats in Mutations |
| 1 | Q9UHJ3 | Scm-like with four MBT domains protein 1 | 866 | 173 173 F->A: Reduced histone-binding 180 180 W->A: Abolishes histone-binding 196 196 Y->A: Reduced histone-binding | Y | |
| 2 | Q9Y468 | Lethal | 840 | 316 316 D->N: Does not affect binding to monomethylated and dimethylated peptides 340 340 F->A: Does not affect binding to monomethylated and dimethylated peptides 423 423 D->A: Abolishes binding to monomethylated and dimethylated peptides 423 423 D->N: Strongly impairs binding to monomethylated and dimethylated peptides 426 426 N->A: Abolishes binding to monomethylated and dimethylated peptides 426 426 N->Q: Strongly impairs binding to monomethylated and dimethylated peptides 431 431 C->F,R: Strongly impairs binding to monomethylated and dimethylated peptides 447 447 F->A: Abolishes binding to monomethylated and dimethylated peptides 450 450 W->L: Abolishes binding to p53/TP53 monomethylated at 'Lys-382' 454 454 Y->L: Abolishes binding to p53/TP53 monomethylated at 'Lys-382' 527 527 D->N: Does not affect binding to monomethylated and dimethylated peptides 551 551 F->A: Does not affect binding to monomethylated and dimethylated peptides | Y | |