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Details of 1 SURP Repeats and their Mutations

S.NOUniprot ID Protein Name Sequence LengthSURP Repeats regionMutationsInvolvement of Repeats in Mutations
1 Q15459 Splicing factor 3A subunit 1 79348 48 E->F: SLURP 1 motif acquires binding to SF3A3
when associated with Leu-55
55 55 K->L: SLURP 1 motif acquires binding to SF3A3
when associated with Phe-48
162 162 F->E: No effect on binding to SF3A3
169 169 L->K: Abolishes binding to SF3A3
Y