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O43493 Proteins with OtherRepeats Repeats

Uniprot ID: O43493	Protein name : Trans-Golgi network integral membrane protein 2	Gene : TGOLN2 TGN46 TGN51
Protein Families :	Squence Length : 479

Sequence	>O43493 480 MRFVVALVLLNVAAAGAVPLLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAESSHFFAYLVTAAILVAVLYIAHHNKRKIIAFVLEGKRSKVTRRPKASDYQRLDQKYVLILNVFPAPPKRSFFPVLTEWYIPLEKDERHQWIVLLSFQL
Repeat regions	REPEAT 54 67 1 REPEAT 68 81 2 REPEAT 82 95 3 REPEAT 96 109 4 REPEAT 110 123 5 REPEAT 124 137 6 REPEAT 138 151 7 REPEAT 152 165 8 REPEAT 166 179 9 REPEAT 180 193 10 REPEAT 194 207 11 REPEAT 208 221 12 REPEAT 222 234 13 REPEAT 235 249 14
Sequence region of repeats	54- 67 SHPEPQTPKDSPSK 68- 81 SSAEAQTPEDTPNK 82- 95 SGAEAKTQKDSSNK 96- 109 SGAEAKTQKGSTSK 110- 123 SGSEAQTTKDSTSK 124- 137 SHPELQTPKDSTGK 138- 151 SGAEAQTPEDSPNR 152- 165 SGAEAKTQKDSPSK 166- 179 SGSEAQTTKDVPNK 180- 193 SGADGQTPKDGSSK 194- 207 SGAEDQTPKDVPNK 208- 221 SGAEKQTPKDGSNK 222- 234 SGAEEQGPIDGPS 235- 249 KSGAEEQTSKDSPNK
Function	May be involved in regulating membrane traffic to and from trans-Golgi network
Motifs	MOTIF 430 433 Endocytosis signal. in isoform TGN46 and isoform TGN48. MOTIF 437 440 Endocytosis signal. in isoform TGN51. MOTIF 460 463 Endocytosis signal. in isoform TGN51
Mutation	430 430 Y->A: Loss of relocalization to the trans-Golgi