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O95171 Proteins with OtherRepeats Repeats
Uniprot ID: O95171
Protein name : Sciellin
Gene : SCEL
Protein Families :
Squence Length : 688
Sequence
>O95171 689 MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGRVVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNRSMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTRRREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNIVKVATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRTDKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGKKDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENISGKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSKIMAKWIP
Repeat regions
REPEAT 251 266 1 REPEAT 267 286 2 REPEAT 287 306 3 REPEAT 307 326 4 REPEAT 327 346 5 REPEAT 347 366 6 REPEAT 367 386 7 REPEAT 387 406 8 REPEAT 407 426 9 REPEAT 427 446 10 REPEAT 447 465 11 REPEAT 466 484 12 REPEAT 485 504 13 REPEAT 505 523 14 REPEAT 524 543 15 REPEAT 544 563 16
Sequence region of repeats
251- 266 ELDNLIKMNKSLNRNQ 267- 286 GLDSLFRANPKVEEREKRAK 287- 306 SLESLIYMSTRTDKDGKGIQ 307- 326 SLGSPIKVNQRTDKNEKGRQ 327- 346 NLESVAKVNARMNKTSRRSE 347- 366 DLDNATEVNPKGHENTTGKK 367- 386 DLDGLIKVDPETNKNITRGQ 387- 406 SLDNLIKVTPEVKRSNQGSK 407- 426 DLNNFIKVYPGTEKSTEGGQ 427- 446 SLDSLIKVTPERNRTNQGNQ 447- 465 DLENLIKVIPSANKSSEQG 466- 484 LDEHINVSPKAVKNTDGKQ 485- 504 DLDKLIKVNPEIFTNNQRNQ 505- 523 DLANLIKVNPAVIRNNQSQ 524- 543 DLDNLIKVKPSALRNTNRDQ 544- 563 NLENLIEVNSHVSENKNGSS
Domains
DOMAIN 619 685 LIM zinc-binding
Function
May function in the assembly or regulation of proteins in the cornified envelope. The LIM domain may be involved in homotypic or heterotypic associations and may function to localize sciellin to the cornified envelope
Mutation