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P23327 Proteins with OtherRepeats Repeats
Uniprot ID: P23327
Protein name : Sarcoplasmic reticulum histidine-rich calcium-binding protein
Gene : HRC HCP
Protein Families : HRC family
Squence Length : 699
Sequence
>P23327 700 MGHHRPWLHASVLWAGVASLLLPPAMTQQLRGDGLGFRNRNNSTGVAGLSEEASAELRHHLHSPRDHPDENKDVSTENGHHFWSHPDREKEDEDVSKEYGHLLPGHRSQDHKVGDEGVSGEEVFAEHGGQARGHRGHGSEDTEDSAEHRHHLPSHRSHSHQDEDEDEVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSHEEDDNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVSTERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEYKTEVPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEGLEEDEPRFTIIPNPLDRREEAGGASSEEESGEDTGPQDAQEYGNYQPGSLCGYCSFCNRCTECESCHCDEENMGEHCDQCQHCQFCYLCPLVCETVCAPGSYVDYFSSSLYQALADMLETPEP
Repeat regions
REPEAT 106 121 2-1 REPEAT 134 154 2-2 REPEAT 155 177 2-3 REPEAT 180 213 1-1 REPEAT 214 237 2-4 REPEAT 238 270 1-2 REPEAT 271 294 2-5 REPEAT 295 318 1-3 REPEAT 319 342 2-6 REPEAT 343 365 1-4
Sequence region of repeats
106- 121 SQDHKVGDEGVSGEEV 134- 154 GHGSEDTEDSAEHRHHLPSHR 155- 177 SHSHQDEDEDEVVSSEHHHHILR 180- 213 HRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHR 214- 237 HRGHGSEEDEDVSDGHHHHGPSHR 238- 270 HQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHR 271- 294 HQGHGIEEDEDVSDGHHHRDPSHR 295- 318 HRSHEEDDNDDDDVSTEYGHQAHR 319- 342 HQDHRKEEVEAVSGEHHHHVPDHR 343- 365 HQGHRDEEEDEDVSTERWHQGPQ
Function
May play a role in the regulation of calcium sequestration or release in the SR of skeletal and cardiac muscle
Mutation