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Q3LI83 Proteins with OtherRepeats Repeats
Uniprot ID: Q3LI83
Protein name : Keratin-associated protein 24-1
Gene : KRTAP24-1 KAP24.1
Protein Families : PMG family
Squence Length : 254
Sequence
>Q3LI83 255 MPAGSMSTTGYPGVCSTTSYRTHCYIPVTSSVTLSSSDLSPTFGHCLPSSYQGNLWLLDYCQESYGEAPTCKSPSCEPKTCSTTGCDPSNSSVPCNSPSAGQVFSVCETTNVSPSPSCSPSTQTNGYVCNCHIPTRNASKACQTLRNGSNCFGQLNCLSKSFQTLNHCRLSTLGYKSYQNPCFIPSYVSPLCYISNSCQPQSYLVRNYHYSSYRPTSCRPLSYLSRSFRSLSYIPSTFPPLRYLCSGSRPLKCY
Repeat regions
REPEAT 193 202 1 REPEAT 203 212 2 REPEAT 213 222 3 REPEAT 223 232 4 REPEAT 233 242 5 REPEAT 243 252 6
Sequence region of repeats
193- 202 SNSCQPQSYL 203- 212 VRNYHYSSYR 213- 222 PTSCRPLSYL 223- 232 SRSFRSLSYI 233- 242 PSTFPPLRYL 243- 252 CSGSRPLKCY
Function
"In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins"
Mutation