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Q5KSL6 Proteins with OtherRepeats Repeats

Uniprot ID: Q5KSL6	Protein name : Diacylglycerol kinase kappa	Gene : DGKK
Protein Families : Eukaryotic diacylglycerol kinase family	Squence Length : 1271

Sequence	>Q5KSL6 1272 MDRGAAAAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSPRTPMSWSRIKKILKEGPMLKNCNSFKRWKLRYFLVQGQKLYFAHHPAFAHFETIDLSQATVAESSCRNLCHSFCVITPQRKITLAAPNRKDMEEWINIIKTIQQGEIYKIPAAENNPFLVGMHCWYSSYSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASKDCKWNTLSITDDLLLPADEVNMPHQWVEGNMPVSSQCAVCHESCGSYQRLQDFRCLWCNSTVHDDCRRRFSKECCFRSHRSSVIPPTALSDPKGDGQLVVSSDFWNLDWSSACSCPLLIFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFARFRILVCGGDGSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLDILNRVEQASVRILDRWSVMIRETPRQTPLLKGQVEMDVPRFEAAAIQHLESAATELNKILKAKYPTEMIIATRFLCSAVEDFVVDIVKAWGQIKQNNTAIVSVILKSDLMYDRLSVLIDVLAEEAAATSAEKSATEYADSSKADRKPFIPQIDHIAKCKLELATKAQSLQKSLKLIIFQVEQALDEESRQTISVKNFSSTFFLEDDPEDINQTSPRRRSRRGTLSSISSLKSEDLDNLNLDHLHFTPESIRFKEKCVMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVHLECDGETISLPNLQGIVVLNITSYAGGINFWGSNTATTEYEAPAIDDGKLEVVAIFGSVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPGLIKIRYKNAAQMLTRDRDFENSMKMWEYKHTEIQAAPQPQLDFQDSQESLSDEEYAQMQHLARLAENLISKLNDLSKIHQHVSVLMGSVNASANILNDIFYGQDSGNEMGAASCIPIETLSRNDAVDVTFSLKGLYDDTTAFLDEKLLRSAEDETALQSALDAMNKEFKKLSEIDWMNPIFVPEEKSSDTDSRSLRLKIKFPKLGKKKVEEERKPKSGQSVQSFIGNLWHRRHREDEAEGDDPLTPSRSQL
Repeat regions	REPEAT 48 51 1 REPEAT 52 55 2 REPEAT 56 59 3 REPEAT 60 63 4 REPEAT 64 67 5 REPEAT 68 71 6 REPEAT 72 75 7 REPEAT 76 79 8 REPEAT 80 83 9 REPEAT 84 87 10 REPEAT 88 91 11 REPEAT 92 95 12 REPEAT 96 99 13 REPEAT 100 103 14 REPEAT 104 107 15 REPEAT 108 111 16 REPEAT 112 115 17 REPEAT 116 119 18 REPEAT 120 123 19 REPEAT 124 127 20 REPEAT 128 131 21 REPEAT 132 135 22 REPEAT 136 139 23 REPEAT 140 143 24 REPEAT 144 147 25 REPEAT 148 151 26 REPEAT 152 155 27 REPEAT 156 159 28 REPEAT 160 163 29 REPEAT 164 167 30 REPEAT 168 171 31 REPEAT 172 175 32 REPEAT 176 179 33
Sequence region of repeats	48- 51 SPEP 52- 55 IPEP 56- 59 CPEL 60- 63 APGP 64- 67 CPEA 68- 71 TSES 72- 75 ATEL 76- 79 YTEP 80- 83 TPEP 84- 87 ATEP 88- 91 ASEP 92- 95 APEP 96- 99 ATEP 100- 103 APEP 104- 107 ATEP 108- 111 APEP 112- 115 APEP 116- 119 ATES 120- 123 APEP 124- 127 TPEP 128- 131 ALES 132- 135 VPEP 136- 139 APEL 140- 143 TPEV 144- 147 APEL 148- 151 APEP 152- 155 TPEP 156- 159 VTEL 160- 163 APEF 164- 167 CPEA 168- 171 APEF 172- 175 RPSP 176- 179 APCL
Domains	DOMAIN 216 309 PH. DOMAIN 487 622 DAGKc
Function	Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA)
Motifs	MOTIF 1269 1271 PDZ-binding
Mutation	78 78 Y->F: Induces a strong reduction in phosphorylation but is still sensitive to H(2)O(2) 1075 1075 Y->F: Does not affect phosphorylation