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Q8WY54 Proteins with OtherRepeats Repeats
Uniprot ID: Q8WY54
Protein name : Protein phosphatase 1E
Gene : PPM1E CAMKN KIAA1072 POPX1
Protein Families : PP2C family
Squence Length : 755
Sequence
>Q8WY54 756 MAGCIPEEKTYRRFLELFLGEFRGPCGGGEPEPEPEPEPEPEPESEPEPEPELVEAEAAEASVEEPGEEAATVAATEEGDQEQDPEPEEEAAVEGEEEEEGAATAAAAPGHSAVPPPPPQLPPLPPLPRPLSERITREEVEGESLDLCLQQLYKYNCPSFLAAALARATSDEVLQSDLSAHYIPKETDGTEGTVEIETVKLARSVFSKLHEICCSWVKDFPLRRRPQLYYETSIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYASIHLHVNLVRQEMFPHDPAEALCRAFRVTDERFVQKAARESLRCGTTGVVTFIRGNMLHVAWVGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVVWFGAWRVNGSLSVSRAIGDAEHKPYICGDADSASTVLDGTEDYLILACDGFYDTVNPDEAVKVVSDHLKENNGDSSMVAHKLVASARDAGSSDNITVIVVFLRDMNKAVNVSEESDWTENSFQGGQEDGGDDKENHGECKRPWPQHQCSAPADLGYDGRVDSFTDRTSLSPGSQINVLEDPGYLDLTQIEASKPHSAQFLLPVEMFGPGAPKKANLINELMMEKKSVQSSLPEWSGAGEFPTAFNLGSTGEQIYRMQSLSPVCSGLENEQFKSPGNRVSRLSHLRHHYSKKWHRFRFNPKFYSFLSAQEPSHKIGTSLSSLTGSGKRNRIRSSLPWRQNSWKGYSENMRKLRKTHDIPCPDLPWSYKIE
Repeat regions
REPEAT 31 32 1 REPEAT 33 34 2 REPEAT 35 36 3 REPEAT 37 38 4 REPEAT 39 40 5 REPEAT 41 42 6 REPEAT 43 44 7 REPEAT 45 46 8 approximate REPEAT 47 48 9 REPEAT 49 50 10 REPEAT 51 52 11
Sequence region of repeats
31- 32 PE 33- 34 PE 35- 36 PE 37- 38 PE 39- 40 PE 41- 42 PE 43- 44 SE 45- 46 PE - A 47- 48 PE 49- 50 PE 51- 52 LV
Domains
DOMAIN 231 488 PPM-type phosphatase
Function
Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2 (By similarity). Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Dephosphorylates PRKAA2 (By similarity)
Mutation