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Q9BYQ8 Proteins with OtherRepeats Repeats
Uniprot ID: Q9BYQ8
Protein name : Keratin-associated protein 4-9
Gene : KRTAP4-9 KAP4.9 KRTAP4.9
Protein Families : KRTAP type 4 family
Squence Length : 210
Sequence
>Q9BYQ8 211 MVSSCCGSVCSDQGCGQDLCQETCCRPSCCETTCCRTTCCRPSCCVSSCCRPQCCQSVCCQPTCSRPSCCQTTCCRTTCYRPSCCVSSCCRPQCCQPACCQPTCCRPSCCETTCCHPRCCISSCCRPSCCVSSCCKPQCCQSVCCQPNCCRPSCSISSCCRPSCCESSCCRPCCCVRPVCGRVSCHTTCYRPTCVISSCPRPLCCASSCC
Repeat regions
REPEAT 24 28 1 REPEAT 29 33 2 REPEAT 34 38 3 REPEAT 39 43 4 REPEAT 44 48 5 REPEAT 49 53 6 REPEAT 54 58 7 REPEAT 59 63 8 REPEAT 69 73 9 REPEAT 74 78 10 REPEAT 84 88 12 REPEAT 89 93 13 REPEAT 94 98 14 REPEAT 99 103 15 REPEAT 104 108 16 REPEAT 109 113 17 REPEAT 114 118 18 REPEAT 119 123 19 REPEAT 124 128 20 REPEAT 129 133 21 REPEAT 134 138 22 REPEAT 139 143 23 REPEAT 144 148 24 REPEAT 149 153 25 REPEAT 159 163 26 REPEAT 164 168 27 REPEAT 169 173 28 REPEAT 174 178 29
Sequence region of repeats
24- 28 RPSCC 29- 33 ETTCC 34- 38 RTTCC 39- 43 RPSCC 44- 48 VSSCC 49- 53 RPQCC 54- 58 QSVCC 59- 63 QPTCS 69- 73 QTTCC 74- 78 RTTCY 84- 88 VSSCC 89- 93 RPQCC 94- 98 QPACC 99- 103 QPTCC 104- 108 RPSCC 109- 113 ETTCC 114- 118 HPRCC 119- 123 ISSCC 124- 128 RPSCC 129- 133 VSSCC 134- 138 KPQCC 139- 143 QSVCC 144- 148 QPNCC 149- 153 RPSCS 159- 163 RPSCC 164- 168 ESSCC 169- 173 RPCCC 174- 178 VRPVC
Function
"In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins"
Mutation