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Q9BYR2 Proteins with OtherRepeats Repeats
Uniprot ID: Q9BYR2
Protein name : Keratin-associated protein 4-5
Gene : KRTAP4-5 KAP4.5 KRTAP4.5
Protein Families : KRTAP type 4 family
Squence Length : 181
Sequence
>Q9BYR2 182 MVSSCCGSVSSEQSCGLENCCRPSCCQTTCCRTTCCRPSCCKPQCCQSVCYQPTCCHPSCCISSCCRPYCCESSCCRPCCCQTTCCRTTCCRTTCCCPSCCVSSCCRPQCCQSVCCQPTCCRPSCCISSCCHPSCCESSCCRPCCCVRPVCGRVSCHTTCYRPTCVISTCPRPLCCASSCC
Repeat regions
REPEAT 5 9 1 REPEAT 20 24 2 REPEAT 25 29 3 REPEAT 30 34 4 REPEAT 35 39 5 REPEAT 40 44 6 REPEAT 45 49 7 REPEAT 55 59 8 REPEAT 60 64 9 REPEAT 65 69 10 REPEAT 70 74 11 REPEAT 75 79 12 REPEAT 80 84 13 REPEAT 85 89 14 REPEAT 90 94 15 REPEAT 95 99 16 REPEAT 100 104 17 REPEAT 105 109 18 REPEAT 110 114 19 REPEAT 115 119 20 REPEAT 120 124 21 REPEAT 125 129 22 REPEAT 130 134 23 REPEAT 135 139 24 REPEAT 140 144 25 REPEAT 145 149 26
Sequence region of repeats
5- 9 GSVSS 20- 24 RPSCC 25- 29 QTTCC 30- 34 RTTCC 35- 39 RPSCC 40- 44 KPQCC 45- 49 QSVCY 55- 59 HPSCC 60- 64 ISSCC 65- 69 RPYCC 70- 74 ESSCC 75- 79 RPCCC 80- 84 QTTCC 85- 89 RTTCC 90- 94 RTTCC 95- 99 CPSCC 100- 104 VSSCC 105- 109 RPQCC 110- 114 QSVCC 115- 119 QPTCC 120- 124 RPSCC 125- 129 ISSCC 130- 134 HPSCC 135- 139 ESSCC 140- 144 RPCCC 145- 149 VRPVC
Function
"In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins"
Mutation