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Q9UPI3 Proteins with OtherRepeats Repeats

Uniprot ID: Q9UPI3	Protein name : Feline leukemia virus subgroup C receptor-related protein 2	Gene : FLVCR2 C14orf58
Protein Families : "Major facilitator superfamily, Feline leukemia virus subgroup C receptor (TC 2.A.1.28.1) family"	Squence Length : 526

Sequence	>Q9UPI3 527 MVNEGPNQEESDDTPVPESALQADPSVSVHPSVSVHPSVSINPSVSVHPSSSAHPSALAQPSGLAHPSSSGPEDLSVIKVSRRRWAVVLVFSCYSMCNSFQWIQYGSINNIFMHFYGVSAFAIDWLSMCYMLTYIPLLLPVAWLLEKFGLRTIALTGSALNCLGAWVKLGSLKPHLFPVTVVGQLICSVAQVFILGMPSRIASVWFGANEVSTACSVAVFGNQLGIAIGFLVPPVLVPNIEDRDELAYHISIMFYIIGGVATLLLILVIIVFKEKPKYPPSRAQSLSYALTSPDASYLGSIARLFKNLNFVLLVITYGLNAGAFYALSTLLNRMVIWHYPGEEVNAGRIGLTIVIAGMLGAVISGIWLDRSKTYKETTLVVYIMTLVGMVVYTFTLNLGHLWVVFITAGTMGFFMTGYLPLGFEFAVELTYPESEGISSGLLNISAQVFGIIFTISQGQIIDNYGTKPGNIFLCVFLTLGAALTAFIKADLRRQKANKETLENKLQEEEEESNTSKVPTAVSEDHL
Repeat regions	REPEAT 25 30 1 REPEAT 31 36 2 REPEAT 37 42 3 REPEAT 43 48 4 REPEAT 49 54 5 REPEAT 55 60 6 approximate REPEAT 61 66 7 approximate REPEAT 67 72 8
Sequence region of repeats	25- 30 VSVHPS 31- 36 VSVHPS 37- 42 VSINPS 43- 48 VSVHPS 49- 54 SSAHPS 55- 60 ALAQPS - V 61- 66 GLAHPS - V 67- 72 SSGPED
Function	"Acts as an importer of heme. Also acts as a transporter for a calcium-chelator complex, important for growth and calcium metabolism"
Mutation
Disease	"DISEASE: Proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome (PVHH) [MIM:225790]: A rare prenatally lethal disorder characterized by hydranencephaly, a distinctive glomerular vasculopathy in the central nervous system and retina, and diffuse ischemic lesions of the brain stem, basal ganglia, and spinal cord with calcifications Hydranencephaly is a condition where the greater portions of the cerebral hemispheres and corpus striatum are replaced by cerebrospinal fluid and glial tissue Note=The disease is caused by mutations affecting the gene represented in this entry"