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Q9Y5V3 Proteins with OtherRepeats Repeats
Uniprot ID: Q9Y5V3
Protein name : Melanoma-associated antigen D1
Gene : MAGED1 NRAGE PP2250 PRO2292
Protein Families :
Squence Length : 778
Sequence
>Q9Y5V3 779 MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQTPPARQSPPARQTPPAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTDWPLPPDWIPADWPIPPDWQNLRPSPNLRPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAEARTRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNARSRFPQTFAGPIIGPGGTASANFAANFGAIGFFWVE
Repeat regions
REPEAT 296 301 1 REPEAT 302 307 2 REPEAT 308 313 3 REPEAT 332 337 4 REPEAT 338 343 5 REPEAT 344 349 6 REPEAT 350 355 7 REPEAT 356 361 8 REPEAT 362 367 9 REPEAT 368 373 10 REPEAT 374 379 11 REPEAT 380 385 12 REPEAT 386 391 13 REPEAT 392 397 14 REPEAT 398 403 15 REPEAT 404 409 16 REPEAT 410 415 17 REPEAT 416 421 18 REPEAT 422 427 19 REPEAT 428 432 20 approximate REPEAT 433 438 21 REPEAT 439 444 22
Sequence region of repeats
296- 301 TPLAWQ 302- 307 NPSGWQ 308- 313 NQTARQ 332- 337 NPVAWQ 338- 343 NPVIWP 344- 349 NPVIWQ 350- 355 NPVIWP 356- 361 NPIVWP 362- 367 GPVVWP 368- 373 NPLAWQ 374- 379 NPPGWQ 380- 385 TPPGWQ 386- 391 TPPGWQ 392- 397 GPPDWQ 398- 403 GPPDWP 404- 409 LPPDWP 410- 415 LPPDWP 416- 421 LPTDWP 422- 427 LPPDWI 428- 432 PADWP - A 433- 438 IPPDWQ 439- 444 NLRPSP
Domains
DOMAIN 471 669 MAGE
Function
"Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rhythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed"
Mutation