| S.NO | Uniprot ID | Protein Name | Sequence Length | DEP Repeated Region | Function |
| 1 | Q70Z35 | "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein " | 1606 | "Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase". | |
| 2 | Q8TB45 | DEP domain-containing mTOR-interacting protein | 409 | Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes. | |
| 3 | Q8TCU6 | "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein " | 1659 | "Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils". |