S.NO | Uniprot ID | Protein Name | Sequence Length | L27 Repeated Region | Function |
1 | Q5T2T1 | MAGUK p55 subfamily member 7 | 576 | Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact. | |
2 | O14936 | Peripheral plasma membrane protein CASK | 926 | "Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4. 1". | |
3 | Q8N3R9 | MAGUK p55 subfamily member 5 | 675 | May play a role in tight junctions biogenesis and in the establishment of cell polarity in epithelial cells. May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter. Required for localization of EZR to the apical membrane of parietal cells and may play a role in the dynamic remodeling of the apical cytoskeleton (By similarity). | |
4 | Q96JB8 | MAGUK p55 subfamily member 4 | 637 | May play a role in retinal photoreceptors development. | |
5 | Q14168 | MAGUK p55 subfamily member 2 | 576 | "Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules to core components of the postsynaptic density (By similarity). In CA1 pyramidal neurons, required for synaptic KCNN2-containing channel function and long-term potentiation expression (By similarity). Seems to negatively regulate SRC function in epithelial cells (PubMed:19665017)". |