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P49746 Proteins with TSP Repeats

Uniprot ID: P49746	Protein name : Thrombospondin-3	Gene : THBS3 TSP3
Protein Families : Thrombospondin family	Squence Length : 956

Sequence	>P49746 957 METQELRGALALLLLCFFTSASQDLQVIDLLTVGESRQMVAVAEKIRTALLTAGDIYLLSTFRLPPKQGGVLFGLYSRQDNTRWLEASVVGKINKVLVRYQREDGKVHAVNLQQAGLADGRTHTVLLRLRGPSRPSPALHLYVDCKLGDQHAGLPALAPIPPAEVDGLEIRTGQKAYLRMQGFVESMKIILGGSMARVGALSECPFQGDESIHSAVTNALHSILGEQTKALVTQLTLFNQILVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQRSHCSPNPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPARTCHSPAHSPCHIHAHCLFERNGAVSCQCNVGWAGNGNVCGTDTDIDGYPDQALPCMDNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQATPFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSYRWQLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTVPEDFEPFRRQLLQGRV
Repeat regions	REPEAT 457 491 TSP type-3 1 REPEAT 492 527 TSP type-3 2 REPEAT 528 550 TSP type-3 3 REPEAT 551 586 TSP type-3 4 REPEAT 587 609 TSP type-3 5 REPEAT 610 647 TSP type-3 6 REPEAT 648 687 TSP type-3 7 REPEAT 688 723 TSP type-3 8
Sequence region of repeats	457- 491 TDIDGYPDQALPCMDNNKHCKQDNCLLTPNSGQED 492- 527 ADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQN 528- 550 SDTDSFGDACDNCPNVPNNDQKD 551- 586 TDGNGEGDACDNDVDGDGIPNGLDNCPKVPNPLQTD 587- 609 RDEDGVGDACDSCPEMSNPTQTD 610- 647 ADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLD 648- 687 SDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPNPNQKD 688- 723 SDGNGVGDVCEDDFDNDAVVDPLDVCPESAEVTLTD
Domains	DOMAIN 23 193 Laminin G-like. DOMAIN 316 354 EGF-like 1. calcium-binding. DOMAIN 370 410 EGF-like 2. calcium-binding. DOMAIN 414 456 EGF-like 3. DOMAIN 727 941 TSP C-terminal
Function	"Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen"