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P58546 Proteins with ANK Repeats
Uniprot ID: P58546
Protein name : Myotrophin
Gene : MTPN
Protein Families : Myotrophin family
Squence Length : 118
Sequence
>P58546 119 MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAFEATDNQAIKALLQ
Repeat regions
REPEAT 2 30 ANK 1 REPEAT 34 66 ANK 2 REPEAT 67 99 ANK 3
Sequence region of repeats
2- 30 KEFMWALKNGDLDEVKDYVAKGEDVNRTL 34- 66 RKPLHYAADCGQLEILEFLLLKGADINAPDKHH 67- 99 ITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDG
Function
"Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity (By similarity). Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy"