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Q9UJT9 Proteins with LRR Repeats

Uniprot ID: Q9UJT9	Protein name : F-box/LRR-repeat protein 7	Gene : FBXL7 FBL6 FBL7 KIAA0840
Protein Families : FBXL7 family	Squence Length : 491

Sequence	>Q9UJT9 492 MGANNGKQYGSEGKGSSSISSDVSSSTDHTPTKAQKNVATSEDSDLSMRTLSTPSPALICPPNLPGFQNGRGSSTSSSSITGETVAMVHSPPPTRLTHPLIRLASRPQKEQASIDRLPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQTLNVQDCEVSVEALRFVKRHCKRCVIEHTNPAFF
Repeat regions	REPEAT 170 195 LRR 1 REPEAT 196 221 LRR 2 REPEAT 222 247 LRR 3 REPEAT 253 281 LRR 4 REPEAT 282 307 LRR 5 REPEAT 308 333 LRR 6 REPEAT 334 359 LRR 7 REPEAT 360 385 LRR 8 REPEAT 386 411 LRR 9 REPEAT 412 437 LRR 10 REPEAT 438 463 LRR 11
Sequence region of repeats	170- 195 VLTRRLCQDTPNVCLMLETVTVSGCR 196- 221 RLTDRGLYTIAQCCPELRRLEVSGCY 222- 247 NISNEAVFDVVSLCPNLEHLDVSGCS 253- 281 SLTREASIKLSPLHGKQISIRYLDMTDCF 282- 307 VLEDEGLHTIAAHCTQLTHLYLRRCV 308- 333 RLTDEGLRYLVIYCASIKELSVSDCR 334- 359 FVSDFGLREIAKLESRLRYLSIAHCG 360- 385 RVTDVGIRYVAKYCSKLRYLNARGCE 386- 411 GITDHGVEYLAKNCTKLKSLDIGKCP 412- 437 LVSDTGLECLALNCFNLKRLSLKSCE 438- 463 SITGQGLQIVAANCFDLQTLNVQDCE
Domains	DOMAIN 111 157 F-box
Function	"Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of AURKA during mitosis, causing mitotic arrest"