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P19883 Proteins Kazal-like domain Repeats
Uniprot ID:P19883
Protein name: Follistatin
Gene : FST
Protein Family:
Squence Length : 344
Sequnce
>P19883 345 MVRARHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGRLSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCNSISEDTEEEEEDEDQDYSFPISSILEW
Domains
DOMAIN 30 103 TB DOMAIN 94 117 Follistatin-like 1 DOMAIN 112 166 Kazal-like 1 DOMAIN 167 190 Follistatin-like 2 DOMAIN 186 241 Kazal-like 2 DOMAIN 244 268 Follistatin-like 3 DOMAIN 264 318 Kazal-like 3
Kazal-like sequence regions
112 - 166 PRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTC 186 - 241 YCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAK 264 - 318 RCSLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCNSIS
Function
Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH)