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P25800 Proteins LIM zinc-binding domain Repeats
Uniprot ID:P25800
Protein name: Rhombotin-1
Gene : LMO1 RBTN1 RHOM1 TTG1
Protein Family:
Squence Length : 156
Sequnce
>P25800 157 MMVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
Domains
DOMAIN 24 83 LIM zinc-binding 1 DOMAIN 88 147 LIM zinc-binding 2
LIM zinc-binding sequence regions
24 - 83 GCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTT 88 - 147 ACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQMDYEEGQLNG
Function
May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors
Disease
"DISEASE: Note=A chromosomal aberration involving LMO1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL) Translocation t(11,14)(p15;q11) with TCRD"