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P46109 Proteins SH3 domain Repeats
Uniprot ID:P46109
Protein name: Crk-like protein
Gene : CRKL
Protein Family:CRK family
Squence Length : 303
Sequnce
>P46109 304 MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDENE
Domains
DOMAIN 14 102 SH2 DOMAIN 123 183 SH3 1 DOMAIN 235 296 SH3 2
SH3 sequence regions
123 - 183 LEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSS 235 - 296 PVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQN
Function
May mediate the transduction of intracellular signals
Mutation
160 160 W->L: Abolishes interaction with DOCK5