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Q9UIK5 Proteins Kazal-like domain Repeats
Uniprot ID:Q9UIK5
Protein name: Tomoregulin-2
Gene : TMEFF2 HPP1 TENB2 TPEF UNQ178/PRO204
Protein Family:Tomoregulin family
Squence Length : 374
Sequnce
>Q9UIK5 375 MVLWESPRQCSSWTLCEGFCWLLLLPVMLLIVARPVKLAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNNDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDAGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI
Domains
DOMAIN 85 137 Kazal-like 1 DOMAIN 176 229 Kazal-like 2 DOMAIN 261 301 EGF-like
Kazal-like sequence regions
85 - 137 VTCVCQFKCNNDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDA 176 - 229 VWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNT
Function
"May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation"