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Q9Y561 Proteins LDL-receptor class A domain Repeats
Uniprot ID:Q9Y561
Protein name: Low-density lipoprotein receptor-related protein 12
Gene : LRP12 ST7
Protein Family:LDLR family
Squence Length : 859
Sequnce
>Q9Y561 860 MACRWSTKESPRWRSALLLLFLAGVYGNGALAEHSENVHISGVSTACGETPEQIRAPSGIITSPGWPSEYPAKINCSWFIRANPGEIITISFQDFDIQGSRRCNLDWLTIETYKNIESYRACGSTIPPPYISSQDHIWIRFHSDDNISRKGFRLAYFSGKSEEPNCACDQFRCGNGKCIPEAWKCNNMDECGDSSDEEICAKEANPPTAAAFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDVPTCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYGDYVKIYDGLEENPHKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDETNCTMCQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETQLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSVRLPMAGRSSNIWNRIFNFARSRHSGSLALVSADGDEVVPSQSTSREPERNHTHRSLFSVESDDTDTENERRDMAGASGGVAAPLPQKVPPTTAVEATVGACASSSTQSTRGGHADNGRDVTSVEPPSVSPARHQLTSALSRMTQGLRWVRFTLGRSSSLSQNQSPLRQLDNGVSGREDDDDVEMLIPISDGSSDFDVNDCSRPLLDLASDQGQGLRQPYNATNPGVRPSNRDGPCERCGIVHTAQIPDTCLEVTLKNETSDDEALLLC
Domains
DOMAIN 47 159 CUB 1 DOMAIN 165 201 LDL-receptor class A 1 DOMAIN 214 255 LDL-receptor class A 2 DOMAIN 259 372 CUB 2 DOMAIN 374 411 LDL-receptor class A 3 DOMAIN 412 449 LDL-receptor class A 4 DOMAIN 450 486 LDL-receptor class A 5
LDL-receptor class A sequence regions
165 - 201 ACDQFRCGNGKCIPEAWKCNNMDECGDSSDEEICAKE 214 - 255 AYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDVP 374 - 411 LPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDETNCTMC 412 - 449 QKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFC 450 - 486 QPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVI
Function
"Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor"