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The Q9UBG3 Proteins with novel repeats
Uniprot ID:Q9UBG3
Gene name: CRNN C1orf10 DRC1 PDRC1 SEP53
Protein Family:S100-fused protein family
Protein name: Cornulin
Length : 495
Sequnce
>Q9UBG3 496 MPQLLQNINGIIEAFRRYARTEGNCTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRLLDEDHTGTVEFKEFLVLVFKVAQACFKTLSESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRGITARELYSYLRSTKP
T-REKS Repeated Sequence regions
Length: 60 residues : 3 times from 241 to 416 :0.6714975845410628 region Length:176 TVEQD-SS---HQTGRTSKQTQE-ATND-QNRGTETHGQGRSQT-SQ-AVTGGHA-QIQAGTHTQTPTQ TVEQD-SS---HQTGSTSTQTQE-STNG-QNRGTEIHGQGRSQT-SQ-AVTGGHT-QIQAGSHTE---- TVEQDRSQTVSHG-GAREQGQTQTQPGSGQ-RWMQVSNPEAGETVPGGQAQTGASTE------SGRQ-E
XSTREAM Repeated Sequence regions
Repeat Length:60; Regions:239-358 TQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTP TQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETV
Domains
DOMAIN 49 84 EF-hand
Function
"Survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When overexpressed in oral squamous carcinom cell lines, regulates negatively cell proliferation by the induction of G1 arrest"
Calcium Binding
CA_BIND 62 73 high affinity