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P20396 Proteins with novel repeats
Uniprot ID:P20396
Gene name: TRH
Protein Family:TRH family
Protein name: Pro-thyrotropin-releasing hormone
Length : 242
Sequnce
>P20396 243 MPGPWLLLALALTLNLTGVPGGRAQPEAAQQEAVTAAEHPGLDDFLRQVERLLFLRENIQRLQGDQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQHPGKRALGGPCGPQGAYGQAGLLLGLLDDLSRSQGAEEKRQHPGRRAAWVREPLEE
Repeated Sequence regions
Length: 17 residues : 2 times from 133 to 166 :0.7631578947368421 region Length:34 KRQHPGRR-S-PWLAYAVP KRQHPGRRLADP-KAQR-S
Function
"As a component of the hypothalamic-pituitary-thyroid axis, it controls the secretion of thyroid-stimulating hormone (TSH) and is involved in thyroid hormone synthesis regulation. It also operates as modulator of hair growth. It promotes hair-shaft elongation, prolongs the hair cycle growth phase (anagen) and antagonizes its termination (catagen) by TGFB2. It stimulates proliferation and inhibits apoptosis of hair matrix keratinocytes"