S.NO | Uniprot ID | Protein Name | Sequence Length | GoLoco Region | Mutation | Involvement of Repeats in Mutations |
1 | P81274 | G-protein-signaling modulator 2 | 684 | 228 228 R->A: Abolishes location at mitotic spindle poles when associated with A-243 228 228 R->E: Strongly reduces interaction with INSC when associated with R-290 243 243 R->A: Abolishes location at mitotic spindle poles when associated with A-228 290 290 N->R: Abolishes interaction with INSC when associated with E-228 | N | |
2 | Q9Y4H4 | G-protein-signaling modulator 3 | 160 | 121 121 A->D: Restores G(i) alpha binding and GDI activity of the GoLoco 2 domain | Y |