S.NO	Uniprot ID	Protein Name	Sequence Length	SH3 Repeated Region	General Function	Active Site	Binding Site	Motif	Calcium Binding	Nucleotide Binding	Mutation	Disease
1	A8MVU1	Putative neutrophil cytosol factor 1C	366	DOMAIN 132 191 SH3 1 DOMAIN 202 261 SH3 2	Fun	-	-	-	-	-	-	-
2	Q9UKW4	Guanine nucleotide exchange factor VAV3	847	DOMAIN 592 660 SH3 1 DOMAIN 788 847 SH3 2	Fun	-	-	-	-	-	-	-
3	P15498	Proto-oncogene vav	845	DOMAIN 592 660 SH3 1 DOMAIN 782 842 SH3 2	Fun	-	-	-	-	-	Mut	-
4	P52735	Guanine nucleotide exchange factor VAV2	878	DOMAIN 586 652 SH3 1 DOMAIN 816 877 SH3 2	Fun	-	-	-	-	-	-	-
5	A6NI72	Putative neutrophil cytosol factor 1B	391	DOMAIN 157 216 SH3 1 DOMAIN 227 286 SH3 2	Fun	-	-	-	-	-	-	-
6	Q8NFA2	NADPH oxidase organizer 1	376	DOMAIN 163 225 SH3 1 DOMAIN 237 296 SH3 2	Fun	-	-	-	-	-	Mut	-
7	O75791	GRB2-related adapter protein 2	330	DOMAIN 1 56 SH3 1 DOMAIN 271 330 SH3 2	Fun	-	-	-	-	-	-	-
8	P62993	Growth factor receptor-bound protein 2	217	DOMAIN 1 58 SH3 1 DOMAIN 156 215 SH3 2	Fun	-	-	-	-	-	Mut	-
9	Q13588	GRB2-related adapter protein	217	DOMAIN 1 58 SH3 1 DOMAIN 158 217 SH3 2	Fun	-	-	-	-	-	-	-
10	Q96B97	SH3 domain-containing kinase-binding protein 1	665	DOMAIN 1 58 SH3 1 DOMAIN 98 157 SH3 2 DOMAIN 267 328 SH3 3	Fun	-	-	-	-	-	-	-
11	Q9Y5K6	CD2-associated protein	639	DOMAIN 1 59 SH3 1 DOMAIN 108 167 SH3 2 DOMAIN 269 330 SH3 3	Fun	-	-	Motif	-	-	-	Dis
12	O60504	Vinexin	671	DOMAIN 380 439 SH3 1 DOMAIN 454 515 SH3 2 DOMAIN 612 671 SH3 3	Fun	-	-	-	-	-	Mut	-
13	Q86WN1	F-BAR and double SH3 domains protein 1	690	DOMAIN 468 529 SH3 1 DOMAIN 546 609 SH3 2	-	-	-	-	-	-	-	-
14	Q8TEC5	E3 ubiquitin-protein ligase SH3RF2	729	DOMAIN 125 184 SH3 1 DOMAIN 187 252 SH3 2 DOMAIN 380 441 SH3 3	Fun	-	-	-	-	-	Mut	-
15	P46108	Adapter molecule crk	304	DOMAIN 132 192 SH3 1 DOMAIN 235 296 SH3 2	Fun	-	-	-	-	-	Mut	-
16	Q7Z6J0	E3 ubiquitin-protein ligase SH3RF1	888	DOMAIN 134 193 SH3 1 DOMAIN 196 259 SH3 2 DOMAIN 445 506 SH3 3 DOMAIN 829 888 SH3 4	Fun	-	-	-	-	-	Mut	-
17	P46109	Crk-like protein	303	DOMAIN 123 183 SH3 1 DOMAIN 235 296 SH3 2	Fun	-	-	-	-	-	Mut	-
18	O15034	RIMS-binding protein 2	1052	DOMAIN 167 234 SH3 1 DOMAIN 848 916 SH3 2 DOMAIN 952 1019 SH3 3	Fun	-	-	-	-	-	-	-
19	Q8TF17	SH3 domain and tetratricopeptide repeat-containing protein 2	1288	DOMAIN 176 240 SH3 1 DOMAIN 268 331 SH3 2	-	-	-	-	-	-	-	Dis
20	Q8TEJ3	E3 ubiquitin-protein ligase SH3RF3	882	DOMAIN 194 253 SH3 1 DOMAIN 256 319 SH3 2 DOMAIN 464 525 SH3 3 DOMAIN 823 882 SH3 4	Fun	-	-	-	-	-	Mut	-
21	P16333	Cytoplasmic protein NCK1	377	DOMAIN 2 61 SH3 1 DOMAIN 106 165 SH3 2 DOMAIN 190 252 SH3 3	Fun	-	-	-	-	-	Mut	-
22	O43639	Cytoplasmic protein NCK2	380	DOMAIN 2 61 SH3 1 DOMAIN 111 170 SH3 2 DOMAIN 195 257 SH3 3	Fun	-	-	-	-	-	Mut	-
23	Q6XZF7	Dynamin-binding protein	1577	DOMAIN 2 61 SH3 1 DOMAIN 66 126 SH3 2 DOMAIN 145 204 SH3 3 DOMAIN 243 302 SH3 4 DOMAIN 1285 1348 SH3 5 DOMAIN 1513 1576 SH3 6	Fun	-	-	-	-	-	-	-
24	Q15811	Intersectin-1	1721	DOMAIN 740 806 SH3 1 DOMAIN 913 971 SH3 2 DOMAIN 1002 1060 SH3 3 DOMAIN 1074 1138 SH3 4 DOMAIN 1155 1214 SH3 5	Fun	-	-	-	calcium	-	Mut	-
25	Q9NZM3	Intersectin-2	1697	DOMAIN 757 818 SH3 1 DOMAIN 898 956 SH3 2 DOMAIN 981 1039 SH3 3 DOMAIN 1053 1117 SH3 4 DOMAIN 1127 1186 SH3 5	Fun	-	-	-	calcium	-	-	-
26	P19878	Neutrophil cytosol factor 2	526	DOMAIN 240 299 SH3 1 DOMAIN 457 516 SH3 2	Fun	-	-	-	-	-	-	Dis
27	Q96MF2	SH3 and cysteine-rich domain-containing protein 3	364	DOMAIN 247 306 SH3 1 DOMAIN 307 364 SH3 2	Fun	-	-	-	-	-	-	Dis
28	Q99469	SH3 and cysteine-rich domain-containing protein	402	DOMAIN 285 344 SH3 1 DOMAIN 347 402 SH3 2	Fun	-	-	-	-	-	-	-
29	Q6ZMT1	SH3 and cysteine-rich domain-containing protein 2	411	DOMAIN 292 351 SH3 1 DOMAIN 354 411 SH3 2	Fun	-	-	-	-	-	Mut	-
30	A1IGU5	Rho guanine nucleotide exchange factor 37	675	DOMAIN 506 569 SH3 1 DOMAIN 602 665 SH3 2	Fun	-	-	-	-	-	-	-
31	O60229	Kalirin	2985	DOMAIN 1646 1711 SH3 1 DOMAIN 2320 2385 SH3 2	Fun	Active	Bind	-	-	Nucle	Mut	Dis
32	Q9BX66	Sorbin and SH3 domain-containing protein 1	1292	DOMAIN 793 852 SH3 1 DOMAIN 867 928 SH3 2 DOMAIN 1231 1292 SH3 3	Fun	-	-	-	-	-	-	-
33	P14598	Neutrophil cytosol factor 1	390	DOMAIN 156 215 SH3 1 DOMAIN 226 285 SH3 2	Fun	-	-	-	-	-	Mut	Dis
34	Q5TCZ1	SH3 and PX domain-containing protein 2A	1133	DOMAIN 166 225 SH3 1 DOMAIN 266 325 SH3 2 DOMAIN 448 507 SH3 3 DOMAIN 840 899 SH3 4 DOMAIN 1072 1133 SH3 5	Fun	-	-	-	-	-	Mut	-
35	Q5HYK7	SH3 domain-containing protein 19	790	DOMAIN 415 477 SH3 1 DOMAIN 495 554 SH3 2 DOMAIN 571 630 SH3 3 DOMAIN 661 720 SH3 4 DOMAIN 730 789 SH3 5	Fun	-	-	-	-	-	-	-
36	A1X283	SH3 and PX domain-containing protein 2B	911	DOMAIN 152 211 SH3 1 DOMAIN 221 280 SH3 2 DOMAIN 368 427 SH3 3 DOMAIN 850 911 SH3 4	Fun	-	-	-	-	-	-	Dis
37	O15117	FYN-binding protein 1	783	DOMAIN 511 572 SH3 1 DOMAIN 700 768 SH3 2	Fun	-	-	Motif	-	-	-	Dis
38	Q9P0V3	SH3 domain-binding protein 4	963	DOMAIN 55 114 SH3 1 DOMAIN 654 724 SH3 2	Fun	-	-	-	-	-	Mut	-
39	O75962	Triple functional domain protein	3097	DOMAIN 1656 1721 SH3 1 DOMAIN 2551 2616 SH3 2	Fun	Active	Bind	-	-	Nucle	Mut	Dis
40	O95153	Peripheral-type benzodiazepine receptor-associated protein 1	1857	DOMAIN 653 720 SH3 1 DOMAIN 1625 1693 SH3 2 DOMAIN 1764 1831 SH3 3	-	-	-	-	-	-	-	-
41	O94875	Sorbin and SH3 domain-containing protein 2	1100	DOMAIN 863 922 SH3 1 DOMAIN 938 999 SH3 2 DOMAIN 1041 1100 SH3 3	Fun	-	-	-	-	-	-	-
42	O94868	F-BAR and double SH3 domains protein 2	740	DOMAIN 469 530 SH3 1 DOMAIN 567 629 SH3 2	-	-	-	-	-	-	-	-
43	Q9UFD9	RIMS-binding protein 3A	1639	DOMAIN 832 899 SH3 1 DOMAIN 1452 1520 SH3 2 DOMAIN 1569 1636 SH3 3	Fun	-	-	-	-	-	-	-
44	A6NNM3	RIMS-binding protein 3B	1639	DOMAIN 832 899 SH3 1 DOMAIN 1452 1520 SH3 2 DOMAIN 1569 1636 SH3 3	-	-	-	-	-	-	-	-
45	A6NJZ7	RIMS-binding protein 3C	1639	DOMAIN 832 899 SH3 1 DOMAIN 1452 1520 SH3 2 DOMAIN 1569 1636 SH3 3	-	-	-	-	-	-	-	-
46	Q9NXL2	Rho guanine nucleotide exchange factor 38	777	DOMAIN 582 645 SH3 1 DOMAIN 713 776 SH3 2	Fun	-	-	-	-	-	-	-

Statistics of Function & Mutation

Details of Functions & Diseases

40 Functions

9 Diseases

Details of Bindings & Mutations

Details of 46 SH3 Repeats containing proteins